The package of iTree tools can produce vitrual immunopeptidomes based on relevant proteomes or genomes, calculate the similarities or distances of immunopeptidomes, and then build the family tree (intraspecies) or the phylogenetic tree (interspecies). The package contains several scripts that can help you download proteomes, convert them to peptidome, compute distances, and build the immunopeptidome-based tree. You are welcome to download it and have a try.

Download iTree Pack!