| General information | |
| ACovPid: | ACoVP100374 |
| Trivial Name: | Mucroporin-M1 |
| Amino Acids Sequence: | LFRLIKSLIKRLVSAFK |
| Length: | 17 |
| C-Terminal Modification: | None |
| N-Terminal Modification: | None |
| Chemical Modification: | None |
| Peptide Source: | Venom of the scorpion Lychas mucronatus(PMID) : 21620914 |
| Source Description: | Mucroporin is the first cationic host defense peptide from the venom of the scorpion Lychas mucronatus, which was cloned and shown to exhibit specific effects on inhibiting bacteria by our group recently |
| Against Virus: | Severe acute respiratory syndrome coronavirus (SARS-CoV) : 694009 |
| Inhibition Value Type: | EC50 |
| Inhibitory Effect: | 7.12 |
| Inhibitory Unit: | µg/mL |
| Target Domain Name: | |
| Assay: | |
| Assay Description: | For titration of SARS-CoV pseudovirus, diluted SARS-CoV pseudovirus was added to Hela-ACE2 cells in 96-well plates for 6 h at 37 °C and then replaced by fresh growth medium. Sixty hours later, cells were lysed directly on the plates and immediately analyzed for luciferase activity with a luciferase assay system (Promega, Madison, WI) and a Modulus™ microplate multimode reader. The SARS-CoV pseudovirus titer is presented as the luciferase relative light units (RLU). |
| Anti-CoV activity in vivo: | |
| Reference: | 21620914 |
| Comment: | |
| 3D structure: | |
| Structure Experiment Verified: | NO |
| Similar Peptides: | ACoVP100375 ACoVP100376 |